Name: (Thomas)Jung-Woog Shin
Mailing Address : 607 O-Bang Dong, Gimhae, Gyongnam, KOREA, 621-749
Position :
Professor
Dept. of Biomedical Engineering, College of Bioscience and Bioengineering,Inje University, KOREA
Director :
National Research Lab(NRL) of Cellular and Biomechanical Engineering
Educational Backgrounds :
1979.3. - 1983. 2. : BS
Dept. of Mechanical Engineering, Seoul National Univ., KOREA
1985. 9. - 1987.8 : MSME(Majoring in Solid Mechanics)
School of Mechanical Engineering, Georgia Institute of Technology,
Atlanta, GA, USA.
1987. 9. - 1992. 8. : Ph.D.(Majoring in Biomechanics)
School of Mechanical Engineering, Georgia Institute of Technology,
Atlanta, GA, USA.
Thesis “The Mechanical Properties of the Human Cornea”
(Supervisor : Raymond. P. Vito, Ph.D.)
Career Highlights :
2006. 03.- Present : Professor
2000. 3 – 2006. 03. : Associate Professor
1999. 3 – 2000. 02 : Visiting Professor at Duke University(Dept. of Orthopaedics)
1993. 3. – 1999. 2. : Assistant . Professor
Dept. of Biomedical Engineering, Inje Univ., KOREA
1987.9 – 1992.8. : Research Assistant
Biomechanics Lab., School of Mechanical Engineering
Georgia Institute of Technology, Atlanta, GA, USA.
1989. 9 - 1993. 2. : Manager of CAE Division
Jinyoung Technology Ltd.(An authorized distributor of Swanson Analysis Corp. in USA)
Research Areas interested.
1) The effects of mechanical stimuli on cellular responses and tissue regeneration
2) High-throughput system for cell or tissue culture
3) Non-invasive techniques for measuring cellular responses
4) Hybrid-Technology combined with MEMS & NMR
5) Designing various equipments or methodologies for the quantified measurements in relation to biology and tissue engineering
6) Quantitative measurements of adhesive forces of cells to any substrate or cell-to-cell
7) Modeling of biological systems
Awards:
1) Best Engineer Award(2009) : Federation of Busan Science and Technology, 2009
2) Nominated as a distinguished scholar by the President of Inje University, 2009
3) Commendation by Secretary of the Ministry for Health, Welfare and Family Affairs in recognition of Development of Bone Cements, 2007
4) Commendation by the President of Korea Health Industry Development Institute in recognition of Development of Artificial Bone Substitutes, 2006
Selected Publications:
International Journals:
1) TJ Shin, RP Vito, LW Johnson, BE McCarey: The Distribution of Strain in the
Human Cornea. J Biomechanics, 1997, 30(5):497~503
2) GR Tack, SY Lee, SJ Lee, BJ Jun, DH Lim, JW Shin, JK Kim, KC Shin: Prediction of Cement Volume for Vertebroplasty Based on imaging and Biomechaincal Results. KSME internation journal, 2001, 15(7):1041~1050
3) SA Park, JW Shin, YI Yang, YK Kim, KD Park, JW Lee, IH Jo, YJ Kim: In vitro study of osteogenic differentiation of bone marrow atromal cells on heat-treated porcine trabecular bone blocks. Biomaterials, 2003, 25:527~535
4) YJ Kim, JW Shin, KD Park, JW Lee, N Yui, SA Park, KS Jee, JK Kim: A study of compatibility between cells and biopolymeric surfaces through quantitative measurements of adhesive forces. Journal of Biomaterial Science-Polymer edition. 2003, 14(12):1311~1321
5) JW Lee, YH Kim, KD Park, KS Jee, JW Shin, SB Hahn: Importance of integrin B1-mediated cell adhesion on biodegradable polymers under surum depletion in mesenchymal stem cells and chondrocytes. Biomaterials, 2003, 25:1901~1909
6) SB Lee, JW Shin, AS Wineman: An Experimental Study of nonlinear viscoelastic bushing model for axial mode. KSME international journal, 2003, 17(9):324~1331
7) SH Kim, JW Shin, SA Park, YK Kim, MS Park, JM Mok, MI Yang, JW Lee : Chemical, structural properties, and osteoconductive effectiveness of bone block derived from porcine cancellous bone. Journal of Biomedical Materials Research part B: applied Biomaterials, 2004, 48b:69~74
8) SB Kim, YJ Kim, TL Yoon, SA Park, IH Cho, EJ Kim, IA Kim, JW Shin: The characteristics of a hydoroxyapatite-chitosan-PMMA bone cement. Biometerials, 2004, 25:5715~5723
9) SJ Kim, JW Shin, CH Lee, HJ Shin, SH Kim, JH Jeong, JW Lee: Biomechanical comparisons of three different tibial tunnel directions in Posterior cruciate ligament reconstruction: Arthroscopy : The Journal of Arthroscopic and Related Surgery. 2005, l21(3):286~293
10) C Park, YJ Kim, SC Lee, KC An, HJ Shin, CH Lee, CH Kim, JW Shin: An in vitro animal study of the biomechanical responses of anulus fibrosus with aging. SPINE, 2005, 30(10):E259~E265
11) CH Lee, HJ Shin, IH Cho, YM Kang, IA Kim, KD Park, JW Shin: Nanofiber alignment and direction of mechanical strain affect the ECM production of human ACL fibroblast. Biomaterials, 2005, 26:1261~1270
12) HJ Shin, CH Lee, IH Cho, YJ Kim, YJ Lee, IA Kim, KD Park, N YUI, JW Shin: Electrospun PLGA nanofiber scaffolds for articular cartilage reconstruction : mechanical stability, degradation and cellular responses under mechanical stimulation in vitro. J Biomater Sci Polymer Edn, 2006, 17(1-2):1~17
13) HD Park, JW Bae, KD Park, T Ooya, N Yui, JH Jang, DK Han, JW Shin: Surface modification of polyurethane using sulfonated PEG grafted polyrotaxane for improved biocompatibility. Macromolecular Research, 2006, 14(1):73~80
14) IA Kim, SA Park, YJ Kim, SH Kim, HJ Shin, YJ Lee, SG Kang, JW Shin: Effects of mechanical stimuli and microfiber-based substrate on neurite outgrowth and guidance. Journal of Bioscience and Bioengineering, 2006, 101(2):120~126
15) SA Park, IA Kim, YJ Lee, JW Shin, CR Kim, JK Kim, YI Yang, JW Shin: Biological responses of ligament fibroblasts and gene expression profiling on micropatterned silicone substrates subjected to mechanical stimuli. Journal of Bioscience and Bioengineering, 2006, 102(5):402~412
16) SH Kim, YR Choi, MS Park, JW Shin, KD Park, SJ Kim, JW Lee: ERK 1/2 activation in enhanced osteogenesis of human mesenchymal stem cells in poly(lactic-glycolic acid) by cyclic hydrostatic pressure. Journal of Biomedical Materials Research part A, 2007, 80(4):826~836
17) SG Lee, EY An, JB Lee, JC Park, JW Shin, JK Kim: Enhanced cell affinity of poly(d,l-lactic-co-glycolic acid) (50/50) by plasma treatment with β-(1 → 3) (1 → 6)-glucan. Surface & coatings technology, 2007, 201:5128~5131
18) Jie Wei, SJ Heo, DH Kim, SE Kim, YT Hyun, JW Shin: Comparison of physical, chemical and cellular responses to nano- and micro- sized calcium silicate/poly(ε-caprolactone) bioactive composites. Journal of the Royal Society Interface, 2007, 5(23):617~630
19) HJ Kim, JW Bae, CH Kim, JW Lee, JW Shin, KD Park: Acellular matrix of bovine pericardium bound with L-arginine. Biomedical Materials, 2007, 2(3):S111-116
20) HS Yun, SE Kim, YT Hyun, SJ Heo, JW Shin: Three-dimensional mesoporous-giantporous inorganic/organic composite scaffold for tissue engineering. 2007, 19(26):6363~6366
21) KM Park, JW Bae, YK Joung, JW Shin, KD Park: Nanoaggregate of thermosensitive chitosan-Pluronic for sustained release of hydrophobic drug. Colloids Surface B Biointerfaces, 2008, 61(1):1-6
22) YJ Kim, SA Park, YJ Lee, JW Shin, DH Kim, SJ Heo, KD Park, JW Shin: Effects of intermittent hydrostatic pressure on cell adhesive forces and other related parameters under various resting periods. Journal of Biomedical Materials Research part B: applied Biomaterials, 2008, 85b(2):353~360
23) JY Kim, EK Park, SY Kim, JW Shin, DW Cho: Fabrication of SFF based Three-dimensional Scaffold using precise deposition system in tissue engineering. Journal of Micromechanics and Microengineering, 2008, 18(5):1~7
24) SH Han, YH Kim, MS Park, IA Kim, JW Shin, WI Yang, KS Jee, KD Park, GH Ryu, JW Lee: Histological and biomechanical properties of regenerated articular cartilage using chondrogenic bone marrow stromal cells with a PLGA scaffold in vivo. Journal of Biomedical Materials Research part A, 2008, 87(4):850~861
25) HS Yun, SE Kim, YT Hyun, SJ Heo, JW Shin, Hierarchically mesoporous-macroporous bioactive glasses scaffolds for bone tissue regeneration. Journal of Biomedical Materials Research Part B, 2008, 87B:374~380
26) J Wei, F Chen, JW Shin, H Hong, C Dai, J Su,C Liu, Preparation and characterization of bioactive mesoporous wollastonite Polycaprolactone composite scaffold. Biomaterials, 2009, 30:1080~1088
27) SJ Heo, SE Kim, J Wei, YT Hyun, HS Yun, DH Kim, JW Shin, JW Shin: Fabrication and characterization of novel nano- and micro-HA/PCL composite scaffold using a modified rapid prototyping process. Journal of Biomedical Materials Research part A, 2008, 89(1):108-116
28) JW Shin, YJ Lee, SJ Heo, SA Park, SH Kim, YJ Kim, DH Kim, JW Shin: Manufacturing of multi-layered nanofibrous structures composed of polyurethane and poly(ethylene oxide) as potential blood vessel scaffolds, Journal of Biomaterials Science:Polymer Edn. 2009, 20:757-771
29) SJ Heo, SE Kim, J Wei, DH Kim, YT Hyun, HS Yun, HK Kim, TR Yoon, SH Kim, SA Park, JW Shin, JW Shin: In vitro and animal study of novel nano-HA/PCL composite scaffolds fabricated by layer manufacturing process. Tissue Engineering Part A, 2009, 15(5): 977-989
30) J Wei, X Wu, C Liu, J Jia, SJ Heo, SE Kim, YT Hyun, JW Shin: Fabrication of Bioactive Scaffold of Poly(e-Caprolactone) and Nanofiber Wollastonite Composite. Journal of the American Ceramic Society, 2009, 92(5): 1017~1023
31) DH Kim, SH Kim, SJ Heo, JW Shin, SW Lee, SA Park, JW Shin: Enhanced differentiation of mesenchymal stem cells into NP-like cells via 3D co-culturing with mechanical stimulation. Journal of Bioscience and Bioengineering, 2009, 108(1):63~67
32) J Wei, SJ Heo, C Liu, DH Kim, SE Kim, YT Hyun, JW Shin, JW Shin: Preparation and characterization of bioactive calcium silicate and poly(epsilon-caprolactone) nanocomposite for bone tissue regeneration. Journal of Biomedical Materials Research part A, 2009, 90(3), 702-712