2010.24
Publisher:liyzbs Publish Time:Friday, January 14, 2011 Source:NRR |
| Research and Reports |
| Neurodegenerative Diseases and Neuroregeneration |
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Dynamic expression of P-glycoprotein in the CA1, CA3 and dentate gyrus of the rat hippocampus following lithium-pilocarpine-induced status epilepticus Neural Regeneration Research 2010;5(24): 1851 Shuda Chen, Jueqian Zhou, Xiuling Liang, Ziyi Chen, Libai Yang, Liemin Zhou Supported by:the Science and Technology Foundation of Guangdong Province, No. 2009B060700049*, 2008B060600063*; the National Natural Science Foundation of China, No. 10671213 |
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|Abstract|HTML| PDF|Supplementary |Editor's Choice |Article Category|Instruction for Authors|Sample Article|Submission |
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This study verified that high expression of P-glycoprotein was determined in the rat hippocampus at 1 and 60 days following lithium-pilocarpine-induced status epilepticus in the levels of tissue, gene and protein. This indicated that epileptic seizures could induce overexpression of P-glycoprotein. This study sought to investigate the correlation of seizure frequency and P-glycoprotein expression, but positive results were not obtained. | | |
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| Traditional Chinese Medicine and Neuroregeneration |
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Meta-analysis of 20 clinical, randomized, controlled trials of acupuncture for depression Neural Regeneration Research 2010;5(24): 1862 Ling Fan, Wenbin Fu, Nenggui Xu, Jianhua Liu, Aihua Ou, Yanwen Wang Supported by:the National Natural Science Foundation of China, No. 30772828*; the Natural Science Foundation of Guangdong Province, No. 07004846*; the Special Scientific Research Foundation of Ministry of Education for Doctoral Research Project of Combined Program of Colleges and Universities, No. 20094425110005*; the Science and Technology Development Program of Guangdong Provincial Science and Technology Department, No. 2008B030301206 |
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|Abstract|HTML| PDF|Supplementary |Editor's Choice |Article Category|Instruction for Authors|Sample Article|Submission |
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① The present study utilized evidence-based medicine approach to evaluate the clinical evidence for treating depression with acupuncture, providing quantitative evidence for acupuncture in the treatment of depression. ② The present study included a total of 20 high quality randomized controlled trials and 2 787 patients from the aspect of depressive state (depressive symptoms). Through the test of heterogeneity, sensitivity analysis, the calculation of combined effect size and the significant test, the detection of publication bias, the efficacy of acupuncture to treat depression was systematically evaluated. | | |
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Luteolin protects PC12 cells from rotenone-induced apoptosis Neural Regeneration Research 2010;5(24): 1870 Lihong Zhu, Renbin Qi, Huadong Wang, Wei Bi, Zhigang Wang, Qi Zeng, Yanru Zhao, Daxiang Lu Supported by:the grant from the Leading Academic Discipline Program, National 211 Project of Jinan University (the 3rd phase) *; the Science and Technology Project of Guangzhou City, No 2008J1-C181-1*; the Fundamental Research Funds for the Central Universities, No. 21609425 |
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|Abstract|HTML| PDF|Supplementary |Editor's Choice |Article Category|Instruction for Authors|Sample Article|Submission |
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Luteolin protects PC12 cells against rotenone-induced apoptosis by decreasing cleaved caspase-3 expression. This provides evidence for primary neurons in vitro study and application of luteolin in models of Parkinson’s disease. | | |
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Thrombolytic activity of cheonggukjang kinase in recovery from brain damage in a rat cerebral embolic stroke model Neural Regeneration Research 2010;5(24): 1875 Angella M Anthony Jalin, Chae Kwan Lee, Chae Yeon Lee, A Reum Kang, Chung Mu Park, Jae Ho Cha, Jeong Hwan Kim, Soo Woong Lee, Young Sun Song, Jong Tae Lee, Sung Goo Kang Supported by:the National Research Foundation of Korea, funded by the Korean Ministry of Education, Science and Technology, No. 2007-0055330*; Inje University Research Grant (2008) |
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|Abstract|HTML| PDF|Supplementary |Editor's Choice |Article Category|Instruction for Authors|Sample Article|Submission |
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Research Highlights |
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Cheonggukjang kinase (CGK) is not a plasminogen activator, but may acts as a plasmin-like protease that can directly dissolve fibrin clots. CGK may exert neuroprotective effects against cerebral embolic stroke insult. CGK may be more efficacious for clot-dissolving than is r-tPA. | | |
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